Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195663 | 0.82 | GABRA1 (0.62) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL11504087 | 0.82 | GABRA1 (0.62) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL12289139 | 0.82 | GABRA1 (0.54) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL467714 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL30314538 | 0.76 | GABRA1 (0.56) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL9755150 | 0.76 | GABRA1 (0.56) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL5142961 | 0.76 | GABRA1 (0.56) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL9157882 | 0.76 | GABRA1 (0.62) | GABRA1GABRB2TSHRCA2CA1 | |
| SCHEMBL4624079 | 0.75 | TRPA1 (0.43) | TP53LMNAHPGDALDH1A1MAPT | |
| SCHEMBL22576311 | 0.75 | GABRA1 (0.45) | GABRA1GABRB2TSHRCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125908-B1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | CLARIANT SPECIALTY FINE CHEM (FR) | 2008-06-04 | — | — | EP | claimed |
| US-20170121459-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2017-05-04 | — | — | US | disclosed |
| US-9579392-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160144046-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2016-05-26 | — | — | US | disclosed |
| US-9228053-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2016-01-05 | — | — | US | disclosed |
| US-20130280783-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2013-10-24 | — | — | US | disclosed |
| US-8492503-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2013-07-23 | — | — | US | disclosed |
| US-20110230618-A1 | Polymeric Alpha-Hydroxy Aldehyde and Ketone Reagents and Conjugation Method | NEKTAR THERAPEUTICS (US) | 2011-09-22 | — | — | US | disclosed |
| WO-2010030366-A2 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2010-03-18 | — | — | WO | disclosed |
| EP-1125908-B1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | CLARIANT SPECIALTY FINE CHEM (FR) | 2008-06-04 | — | — | EP | disclosed |
| EP-1125908-B1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | CLARIANT SPECIALTY FINE CHEM (FR) | 2008-06-04 | — | — | EP | disclosed |
| CN-1202063-C | Method for preparing novel phenol compound divirated from dialkoxy acetaldehyde | CLANIANT GMBH (FR) | 2005-05-18 | — | — | CN | disclosed |
| US-6774267-B2 | REACTING A PHENOL COMPOUND WITH AN ALDEHYDE CONTAINING DIALKOXYMETHYL OR 1,3-DIOXOLAN-2-YL GROUP IN PRESENCE OF A BASE | CLARIANT FRANCE (FR) | 2004-08-10 | — | — | US | disclosed |
| CN-1337387-A | Method for preparing novel phenol compound divirated from dialkoxy acetaldehyde | CLANIANT GMBH (FR) | 2002-02-27 | — | — | CN | disclosed |
| US-20010016664-A1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | CLARIANT (FRANCE) S.A. | 2001-08-23 | — | — | US | disclosed |
| EP-1125908-A1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | Clariant (France) S.A. (FR) | 2001-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160144046-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | ASPH, ALDH1A1, ADH1C | GABRA1 1284/4885GABRB2 1717/4885TSHR 3391/4885 |
| US-20010016664-A1 | New phenolic compounds derived from dialkoxyethanals, their preparation process and their application | CYC1, CCNY, MT-CO1 | GABRA1 4518/4885GABRB2 4702/4885TSHR 3268/4885 |
| US-20130280783-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | ASPH, ALDH1A1, ADH1C | GABRA1 1284/4885GABRB2 1717/4885TSHR 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.