Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455106 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2ASLC6A9MAOBKDM4E | |
| SCHEMBL1661498 | 0.80 | CACNA2D1 (0.51) | KMT2ASLC6A9KDM4ENPSR1CACNA2D1 | |
| SCHEMBL3421906 | 0.80 | MAPT (0.41) | ALDH1A1KMT2ASLC6A9CYP3A4CYP2D6 | |
| SCHEMBL85386 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KMT2ASLC6A9MAOBKDM4E | |
| SCHEMBL20594076 | 0.76 | KMT2A (0.57) | ALDH1A1KMT2ASLC6A9MAOBCYP3A4 | |
| SCHEMBL29220868 | 0.76 | SLC6A9 (0.44) | ALDH1A1KMT2ASLC6A9MAOBCYP2D6 | |
| SCHEMBL5074961 | 0.76 | KMT2A (0.45) | ALDH1A1KMT2ASLC6A9MAOBMAPT | |
| SCHEMBL4321754 | 0.76 | OPRM1 (0.51) | ALDH1A1KMT2ASLC6A9MAOBCYP3A4 | |
| SCHEMBL16448458 | 0.76 | OPRM1 (0.50) | ALDH1A1KMT2ASLC6A9CYP2D6NPSR1 | |
| SCHEMBL12499368 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KMT2ASLC6A9MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |