Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594076 | 0.87 | KMT2A (0.57) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL12499368 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL3299615 | 0.84 | MAOB (0.53) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL3296944 | 0.84 | SLC6A9 (0.53) | SLC6A9CACNA2D1CACNB1CACNA1CCACNA1A | |
| Hydrochloric Acid SCHEMBL4509686 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL27481210 | 0.83 | CNR1 (0.57) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| Hydrochloric Acid SCHEMBL5394384 | 0.82 | CNR1 (0.56) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL18263730 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KMT2ACNR1CNR2MAOB | |
| SCHEMBL24873255 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL72964 | 0.81 | CYP3A4 (0.49) | ALDH1A1KMT2ACNR1CNR2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068346-A | Dental photocurable composition having excellent handling properties and storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068345-A | Dental adhesive composition having excellent storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | SHOFU INC. (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-4056163-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-14 | — | — | EP | disclosed |
| US-20220117945-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2022-04-21 | — | — | US | disclosed |
| US-20220117945-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2022-04-21 | — | — | US | disclosed |
| EP-3601276-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| EP-3022202-B1 | AUTOTAXIN INHIBITORS COMPRISING A HETEROAROMATIC RING-BENZYL-AMIDE-CYCLE CORE | NOVARTIS AG (CH) | 2019-05-15 | — | — | EP | disclosed |
| US-10183025-B2 | Autotaxin inhibitors | NOVARTIS AG (CH) | 2019-01-22 | — | — | US | disclosed |
| WO-2018172997-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2018-09-27 | — | — | WO | disclosed |
| US-4755210-A | Composition containing 3-carboxyazetidine, water, surfactant | SHELL OIL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4569688-A | N-Formyl-3-carboxyazetidine and its use for sterilizing the male parts of wheat plants | SHELL OIL COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| US-4555260-A | 3-CARBOXYAZETIDINE | SHELL OIL COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4534787-A | SELECTIVE STERILIZING OF MALE PARTS OF WHEAT PLANTS | SHELL OIL COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0029265-B1 | A METHOD FOR PREPARING AZETIDINE DERIVATIVES, MALE STERILITY IN PLANTS PRODUCING COMPOSITIONS CONTAINING THEM, THEIR USE IN STERILIZING MALE PARTS IN PLANTS, A METHOD OF PRODUCING F1 HYBRID SEED AND CERTAIN NOVEL AZETIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-08-17 | — | — | EP | disclosed |
| EP-0029265-A2 | A method for preparing azetidine derivatives, male sterility in plants producing compositions containing them, their use in sterilizing male parts in plants, a method of producing F1 hybrid seed and certain novel azetidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | ITGA1, ITGB1, CDH1 | ALDH1A1 20/4885KMT2A 2406/4885CNR1 2177/4885 |
| US-20220117945-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | SLC26A4, SLC26A3, ALDH5A1 | ALDH1A1 196/4885KMT2A 3481/4885CNR1 455/4885 |
| US-10183025-B2 | Autotaxin inhibitors | ENPP2, SERPINB1, TFPI | ALDH1A1 4843/4885KMT2A 3346/4885CNR1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.