SCHEMBL4680198

SCHEMBL4680198

Cn1nnnc1C(=NO)c1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.40
MAPT P10636 4/20 0.38
HTT P42858 3/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 2/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
RGS12 O14924 1/20 0.33
GAA P10253 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4684160 0.86 ALDH1A1 (0.39) LMNAMAPTHTTTSHRHPGD
SCHEMBL4684225 0.84 ALDH1A1 (0.40) LMNANPSR1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL968342 0.84 HPGD (0.41) LMNAMAPTHTTHPGDNPSR1
SCHEMBL3328603 0.84 HPGD (0.41) LMNAMAPTHTTHPGDNPSR1
SCHEMBL4685242 0.82 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1KDM4ERAB9A
SCHEMBL4686699 0.78 HTT (0.51) LMNAMAPTHTTTSHRHPGD
SCHEMBL14505563 0.75 LMNA (0.38) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL30698221 0.74 HPGD (0.38) LMNAMAPTHTTHPGDNPSR1
SCHEMBL2888801 0.73 ADCY8 (0.34) SMN1; SMN2
SCHEMBL1864420 0.72 SMN1; SMN2 (0.32) MAPTHTTSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426371-B1 TETRAZOYL OXIME DERIVATIVES AND AGROCHEMICALS CONTAINING THE SAME AS THE ACTIVE INGREDIENT NIPPON SODA CO (JP) 2008-12-03 EP disclosed
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD (JP) 2007-05-10 US disclosed
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD (JP) 2007-05-10 US disclosed
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD (JP) 2007-05-10 US disclosed
US-7183299-B2 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD. (JP) 2007-02-27 US disclosed
US-7183299-B2 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD. (JP) 2007-02-27 US disclosed
US-7183299-B2 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD. (JP) 2007-02-27 US disclosed
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-03-31 US disclosed
EP-1426371-A1 TETRAZOYL OXIME DERIVATIVE AND AGRICULTURAL CHEMICAL CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient PAOX, TH, CYP2E1 LMNA 2880/4885MAPT 3704/4885HTT 2610/4885
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient TH, CYP2E1, PAOX LMNA 3005/4885MAPT 3603/4885HTT 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.