Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 3/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888804 | 1.00 | ADCY8 (0.34) | ADCY8ADCY1GPBAR1NOTUMS1PR1 | |
| SCHEMBL1073103 | 0.82 | GPBAR1 (0.40) | ADCY8ADCY1GPBAR1NOTUMDRD4 | |
| SCHEMBL1073884 | 0.81 | SRC (0.33) | SMN1; SMN2 | |
| SCHEMBL1073883 | 0.81 | SRC (0.33) | SMN1; SMN2 | |
| SCHEMBL4684160 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2 | |
| SCHEMBL1071944 | 0.76 | — | — | |
| SCHEMBL4684225 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2 | |
| SCHEMBL14505563 | 0.75 | LMNA (0.38) | — | |
| SCHEMBL1080530 | 0.75 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL1080531 | 0.75 | S1PR1 (0.33) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | HAAO, CYP51A1, HPD | ADCY8 4225/4885ADCY1 4419/4885GPBAR1 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.