SCHEMBL468058

SCHEMBL468058

CN1C=CC=C(C(=O)O)C1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28702490 1.00 TSHR (0.37) TSHRMAPK1HSD17B10TDP1THRB
Iodide SCHEMBL10567947 0.98 TSHR (0.36) TSHRMAPK1HSD17B10TDP1THRB
Water SCHEMBL28685341 0.98 TSHR (0.36) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL27766138 0.84 TSHR (0.32) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1268596 0.83
Acetic Acid SCHEMBL2788321 0.81 TSHR (0.33) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL30514305 0.81
Iodide SCHEMBL3065810 0.80 GABRR1 (0.33) TSHRMAPK1HSD17B10TDP1THRB
Hydrochloric Acid SCHEMBL134284 0.80 THRB (0.34) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL3449675 0.79 BAZ2B (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295624-A1 MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2025-09-25 US claimed
CN-120195298-A Metabolic marker composition for discriminating tobacco grades, screening method and application 哈尔滨脉图精准技术有限公司 2025-06-24 CN claimed
EP-3321686-B1 BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME METABOLON INC (US) 2024-03-13 EP claimed
EP-3554258-B1 COMPOSITIONS AND METHODS THAT MODULATE PHOSPHORUS OR ENZYMES IN A COMPANION ANIMAL NESTLE SA (CH) 2023-07-19 EP claimed
EP-3554263-B1 COMPOSITIONS AND METHODS THAT MODULATE DIGESTIBILITY IN A COMPANION ANIMAL NESTLE SA (CH) 2023-07-19 EP claimed
US-20220003753-A1 METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ADS PHENOTYPE 1 STALICLA SA (CH) 2022-01-06 US claimed
CN-113490489-A Monomethyl fumarate-carrier conjugates and methods of use thereof 旗舰创业创新五公司 2021-10-08 CN claimed
CN-113166811-A Metabolic profiling for diagnosing subtype ASD phenotype 1 in patients with idiopathic autism spectrum disorders 斯大利卡拉公司 2021-07-23 CN claimed
CN-109642337-B Ternary zinc-nickel-iron alloy and alkaline electrolyte for electroplating such an alloy 科文特亚股份有限公司 2021-07-13 CN claimed
US-11040117-B2 Treatment of a subtype of ASD Stalicla S.A. (CH) 2021-06-22 US claimed
EP-1888115-A2 COMPOUNDS FOR PHOTOCHEMOTHERAPY UNIVERSITE DE GENEVE (CH) 2008-02-20 EP claimed
US-20070259861-A1 Combination therapy with non-selective COX inhibitors to prevent COX-related gastric injuries PHARMENA NORTH AMERICA INC. (CA) 2007-11-08 US claimed
WO-2007103540-A2 COMBINATION THERAPY WITH NON-SELECTIVE COX INHIBITORS TO PREVENT COX-RELATED GASTRIC INJURIES PHARMENA NORTH AMERICA INC. (CA) 2007-09-13 WO claimed
WO-2007074406-A2 FORMULATIONS FOR TREATMENT OF LIPOPROTEIN ABNORMALITIES COMPRISING A STATIN A STATIN AND A METHYLNICOTINAMIDE DERIVATIVE PHARMENA NORTH AMERICA INC. (CA) 2007-07-05 WO claimed
WO-2007023398-A2 COMPOUNDS FOR PHOTOCHEMOTHERAPY UNIVERSITE DE GENEVE (US) 2007-03-01 WO claimed
EP-1147086-B1 COMPOSITIONS FOR THE TREATMENT OF SKIN DISEASES TECHNICAL UNIVERSITY OF LODZ (PL) 2005-03-30 EP claimed
US-6403658-B1 Genital vasodilator TOPPO, FRANK 2002-06-11 US claimed
EP-1147086-A1 COMPOSITIONS FOR THE TREATMENT OF SKIN DISEASES Technical University of Lodz (PL) 2001-10-24 EP claimed
WO-2000040559-A1 COMPOSITIONS FOR THE TREATMENT OF SKIN DISEASES TECHNICAL UNIVERSITY OF LODZ (PL) 2000-07-13 WO claimed
US-4332792-A Insect attractant ZOECON CORPORATION (US) 1982-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259861-A1 Combination therapy with non-selective COX inhibitors to prevent COX-related gastric injuries PTGS1, PTGS2, PTGES2 TSHR 3705/4885MAPK1 1725/4885HSD17B10 2592/4885
US-20250295624-A1 MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE SLC16A1, SLC16A3, SLC16A8 TSHR 4607/4885MAPK1 4249/4885HSD17B10 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.