Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4459252 | 0.99 | MAOB (0.49) | MAOBLOXL2MCL1XDHNPC1 | |
| SCHEMBL4684163 | 0.93 | LTA4H (0.47) | MAOBLOXL2MCL1XDHLTA4H | |
| Hydrochloric Acid SCHEMBL4456777 | 0.92 | LTA4H (0.48) | MAOBLOXL2MCL1XDHLTA4H | |
| SCHEMBL4686964 | 0.91 | MCL1 (0.46) | MCL1XDHNPC1RAB9ALTA4H | |
| SCHEMBL4456543 | 0.89 | MCL1 (0.54) | MAOBMCL1XDHNPC1RAB9A | |
| SCHEMBL3270671 | 0.88 | MAOA (0.46) | MAOBMCL1XDHNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4461345 | 0.86 | XDH (0.45) | MAOBMCL1XDHNPC1RAB9A | |
| SCHEMBL4460360 | 0.86 | LTA4H (0.47) | MCL1XDHNPC1RAB9ALTA4H | |
| SCHEMBL4680896 | 0.86 | MAOB (0.49) | MAOBMCL1XDHNPC1RAB9A | |
| SCHEMBL4456749 | 0.85 | PRMT5 (0.43) | MCL1XDHNPC1RAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638943-B1 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2008-08-06 | — | — | EP | claimed |
| JP-2007501267-A | — | — | 2007-01-25 | — | — | JP | claimed |
| EP-1638943-A2 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2006-03-29 | — | — | EP | claimed |
| WO-2004106307-A2 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-12-09 | — | — | WO | claimed |
| EP-1638943-B1 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2008-08-06 | — | — | EP | disclosed |