Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686964 | 0.93 | MCL1 (0.46) | LTA4HMCL1CYP11B1CYP11B2RAB9A | |
| SCHEMBL4456543 | 0.88 | MCL1 (0.54) | PRMT5MCL1RAB9AXDHNPC1 | |
| SCHEMBL4460360 | 0.88 | LTA4H (0.47) | LTA4HMCL1RAB9AXDHNPC1 | |
| SCHEMBL3270671 | 0.87 | MAOA (0.46) | LTA4HMCL1RAB9AXDHNPC1 | |
| SCHEMBL4680696 | 0.87 | MCL1 (0.48) | LTA4HMCL1RAB9AXDHNPC1 | |
| SCHEMBL4455245 | 0.87 | NPC1 (0.50) | LTA4HMCL1RAB9AXDHNPC1 | |
| SCHEMBL4460188 | 0.87 | NPC1 (0.45) | LTA4HMCL1RAB9AXDHNPC1 | |
| Hydrochloric Acid SCHEMBL4461345 | 0.86 | XDH (0.45) | LTA4HMCL1RAB9AXDHNPC1 | |
| SCHEMBL4465047 | 0.86 | PRMT5 (0.42) | PRMT5RAB9ANPC1TP53TSHR | |
| SCHEMBL4680834 | 0.85 | MAOB (0.47) | LTA4HMCL1RAB9AXDHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534805-B2 | Imidazole derivatives, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-05-19 | — | — | US | disclosed |
| EP-1638943-B1 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2008-08-06 | — | — | EP | disclosed |
| US-20070066542-A1 | Novel imidazole derivatives, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066542-A1 | Novel imidazole derivatives, their preparation and their use as medicaments | MIF, MCL1, PPIP5K2 | PRMT5 442/4885LTA4H 3441/4885MCL1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.