Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681552 | 0.90 | NR4A2 (0.49) | PKMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL4684167 | 0.88 | MCL1 (0.50) | PKMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL4685016 | 0.82 | GAA (0.47) | SRD5A2MCL1PPARGMAP4K4 | |
| SCHEMBL4681866 | 0.81 | NR4A2 (0.50) | PKMNR4A2NR4A1NR4A3FFAR1 | |
| SCHEMBL4680831 | 0.81 | RXRA (0.44) | PKMNR4A2NR4A1NR4A3FFAR1 | |
| SCHEMBL4460197 | 0.78 | CYP2D6 (0.52) | — | |
| SCHEMBL4468971 | 0.78 | XDH (0.43) | PKMMCL1 | |
| SCHEMBL5750527 | 0.78 | LMNA (0.44) | MCL1 | |
| SCHEMBL4686964 | 0.78 | MCL1 (0.46) | MCL1 | |
| SCHEMBL4466562 | 0.77 | RAB9A (0.45) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638943-B1 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2008-08-06 | — | — | EP | claimed |