Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.63 |
| ▸ | QPCT | Q16769 | 2/20 | 0.63 |
| ▸ | KDR | P35968 | 6/20 | 0.57 |
| ▸ | FLT3 | P36888 | 5/20 | 0.57 |
| ▸ | PRKCB | P05771 | 3/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 2/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683228 | 0.81 | GSK3B (0.58) | GSK3BQPCTKDRFLT3PRKCB | |
| SCHEMBL4682950 | 0.80 | GSK3B (0.64) | GSK3BQPCTKDRFLT3PRKCB | |
| SCHEMBL4682947 | 0.79 | GSK3B (0.62) | GSK3BQPCTKDRFLT3PRKCB | |
| SCHEMBL8162775 | 0.79 | PRKACA (0.63) | GSK3BKDRFLT3PRKCAPRKACA | |
| SCHEMBL2955240 | 0.74 | GSK3B (0.57) | GSK3BQPCTKDRPRKCBPRKCG | |
| SCHEMBL1127716 | 0.73 | GSK3B (0.64) | GSK3BQPCTKDRPRKCBPRKCG | |
| SCHEMBL4680645 | 0.73 | PRKCG (0.57) | GSK3BQPCTKDRPRKCBPRKCG | |
| SCHEMBL12507154 | 0.73 | KDR (0.85) | GSK3BQPCTKDRFLT3PRKCA | |
| SCHEMBL12607357 | 0.73 | GSK3B (1.00) | GSK3BKDRFLT3PRKCA | |
| SCHEMBL12506836 | 0.73 | GSK3B (1.00) | GSK3BQPCTKDRFLT3PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |