Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.58 |
| ▸ | QPCT | Q16769 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 6/20 | 0.52 |
| ▸ | FLT3 | P36888 | 5/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 2/20 | 0.50 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680883 | 0.81 | GSK3B (0.63) | GSK3BQPCTKDRFLT3PRKCB | |
| SCHEMBL6194938 | 0.76 | CAMK2D (0.44) | GSK3BKDRFLT3CCNE2CDK4 | |
| SCHEMBL4682950 | 0.76 | GSK3B (0.64) | GSK3BQPCTKDRFLT3CDK4 | |
| SCHEMBL4682947 | 0.75 | GSK3B (0.62) | GSK3BQPCTKDRFLT3PRKCB | |
| SCHEMBL8162775 | 0.74 | PRKACA (0.63) | GSK3BKDRFLT3CCNE2CDK4 | |
| SCHEMBL8167809 | 0.74 | CDK2 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL12507154 | 0.71 | KDR (0.85) | GSK3BQPCTKDRFLT3CDK4 | |
| SCHEMBL2955240 | 0.70 | GSK3B (0.57) | GSK3BQPCTKDRCCNE2CDK4 | |
| SCHEMBL1127716 | 0.69 | GSK3B (0.64) | GSK3BQPCTKDRCCNE2CDK4 | |
| SCHEMBL4680645 | 0.69 | PRKCG (0.57) | GSK3BQPCTKDRCDK2PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |