Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681085 | 0.82 | LMNA (0.47) | MC4RLMNAGLATSHR | |
| SCHEMBL4685109 | 0.81 | MC4R (0.42) | MC4RLMNAGLATSHR | |
| SCHEMBL4684460 | 0.81 | MC4R (0.55) | MC4R | |
| SCHEMBL4681339 | 0.80 | MC4R (0.47) | MC4RLMNAGLATSHR | |
| SCHEMBL4515320 | 0.80 | MC4R (0.63) | MC4R | |
| SCHEMBL4681340 | 0.80 | MC4R (0.51) | MC4R | |
| SCHEMBL4677982 | 0.80 | MC4R (0.43) | MC4RLMNAGLATSHR | |
| SCHEMBL4784715 | 0.79 | MC4R (0.45) | MC4RLMNAGLATSHR | |
| SCHEMBL4683042 | 0.78 | MAPT (0.46) | MC4RLMNA | |
| SCHEMBL4521185 | 0.77 | MC4R (0.40) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | disclosed |