Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674540 | 1.00 | HTR4 (0.36) | HTR4C5AR1CACNA1GCACNA1HOPRL1 | |
| SCHEMBL4675602 | 0.87 | CYP3A4 (0.41) | HTR4C5AR1CACNA1GCACNA1HOPRL1 | |
| SCHEMBL4674536 | 0.83 | PTGDR2 (0.35) | HTR4C5AR1CACNA1GCACNA1HOPRL1 | |
| SCHEMBL3398375 | 0.82 | CACNA1G (0.35) | HTR4C5AR1CACNA1GCACNA1HHSD11B1 | |
| SCHEMBL4681962 | 0.82 | OPRL1 (0.46) | C5AR1CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL4681961 | 0.82 | OPRL1 (0.46) | C5AR1CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL4676172 | 0.80 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL4677810 | 0.80 | OPRM1 (0.50) | OPRL1HSD11B1OPRM1OPRK1 | |
| SCHEMBL4677814 | 0.80 | OPRM1 (0.50) | OPRL1HSD11B1OPRM1OPRK1 | |
| SCHEMBL4676169 | 0.80 | HSD11B1 (0.46) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |