Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682266 | 1.00 | DRD2 (0.43) | DRD2SLC6A4USP2KMT2AALDH1A1 | |
| SCHEMBL4674487 | 0.83 | ALDH1A1 (0.45) | USP2KMT2AALDH1A1CCR5KDM4E | |
| SCHEMBL4674486 | 0.83 | ALDH1A1 (0.45) | USP2KMT2AALDH1A1CCR5KDM4E | |
| SCHEMBL4682261 | 0.83 | DRD2 (0.44) | DRD2SLC6A4USP2KMT2AALDH1A1 | |
| SCHEMBL1838649 | 0.81 | DRD2 (0.41) | DRD2SLC6A4USP2KMT2AALDH1A1 | |
| SCHEMBL4678008 | 0.80 | FPR2 (0.43) | KMT2AOPRM1CCR5CYP2C9FPR2 | |
| SCHEMBL4678005 | 0.80 | FPR2 (0.43) | KMT2AOPRM1CCR5CYP2C9FPR2 | |
| SCHEMBL4675602 | 0.79 | CYP3A4 (0.41) | DRD2OPRM1OPRL1 | |
| SCHEMBL1834088 | 0.78 | USP2 (0.48) | DRD2SLC6A4USP2KMT2AALDH1A1 | |
| SCHEMBL1831393 | 0.78 | USP2 (0.48) | DRD2SLC6A4USP2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |