Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674480 | 0.84 | ALDH1A1 (0.44) | KMT2AALDH1A1USP2CCR5HSD17B10 | |
| SCHEMBL4682266 | 0.83 | DRD2 (0.43) | DRD2SLC6A4KMT2AALDH1A1USP2 | |
| SCHEMBL4682269 | 0.83 | DRD2 (0.43) | DRD2SLC6A4KMT2AALDH1A1USP2 | |
| SCHEMBL4678001 | 0.80 | FPR2 (0.42) | CYP2C9OPRM1CCR5FPR2 | |
| SCHEMBL4675596 | 0.79 | CYP3A4 (0.40) | DRD2SLC6A4OPRM1OPRL1CHRM2 | |
| SCHEMBL4676160 | 0.78 | HSD11B1 (0.45) | KMT2AALDH1A1CHRM1 | |
| SCHEMBL3803735 | 0.78 | OPRM1 (0.49) | ALDH1A1CYP2C9OPRM1OPRL1CHRM2 | |
| SCHEMBL4674536 | 0.76 | PTGDR2 (0.35) | OPRM1OPRL1CHRM2CHRM1CHRM3 | |
| SCHEMBL4681956 | 0.76 | OPRL1 (0.48) | OPRM1OPRL1 | |
| SCHEMBL1838649 | 0.75 | DRD2 (0.41) | DRD2SLC6A4KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |