Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688990 | 0.87 | PKM (0.50) | PKMRAB9ATAS1R3TAS1R1MAPT | |
| SCHEMBL4226997 | 0.86 | PKM (0.47) | PKMRAB9ATAS1R3TAS1R1POLB | |
| SCHEMBL4744588 | 0.86 | PKM (0.57) | PKMRAB9ATAS1R3TAS1R1POLB | |
| SCHEMBL4226994 | 0.85 | PKM (0.46) | PKMRAB9ATAS1R3TAS1R1MAPT | |
| SCHEMBL4683265 | 0.84 | EPHX1 (0.46) | PKMRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4237924 | 0.81 | PKM (0.55) | PKMRAB9ATAS1R3TAS1R1POLB | |
| SCHEMBL4236665 | 0.81 | PKM (0.52) | PKMRAB9ATAS1R3TAS1R1POLB | |
| SCHEMBL4233270 | 0.81 | PKM (0.52) | PKMRAB9ATAS1R3TAS1R1POLB | |
| SCHEMBL4236879 | 0.80 | TAS1R3 (0.42) | TAS1R3TAS1R1MAPTSMN1; SMN2HRH3 | |
| SCHEMBL4686514 | 0.79 | RAB9A (0.41) | PKMRAB9APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |