Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MYOC | Q99972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683388 | 1.00 | HSPB1 (0.45) | HSPB1TBXA2RGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4785116 | 0.86 | TBXA2R (0.58) | TBXA2RPOLB | |
| SCHEMBL4226643 | 0.86 | PKM (0.47) | HSPB1TBXA2RGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4684087 | 0.85 | ALDH1A1 (0.47) | TBXA2RGAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4684093 | 0.85 | ALDH1A1 (0.47) | TBXA2RGAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4684505 | 0.83 | HSPB1 (0.50) | HSPB1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4684500 | 0.83 | HSPB1 (0.50) | HSPB1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4683615 | 0.81 | MEN1 (0.51) | TBXA2RGAAALDH1A1HTTL3MBTL1 | |
| SCHEMBL4683610 | 0.81 | MEN1 (0.51) | TBXA2RGAAALDH1A1HTTL3MBTL1 | |
| SCHEMBL4229163 | 0.79 | MAPT (0.53) | HSPB1TBXA2RALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |