SCHEMBL4683467

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4683858	0.91	ALDH1A1 (0.50)	ALDH1A1MAPTNPSR1SMN1; SMN2RAB9A
	SCHEMBL4682172	0.89	MAPT (0.56)	ALDH1A1MAPTNPSR1SMN1; SMN2RAB9A
	SCHEMBL5218080	0.88	ALDH1A1 (0.61)	ALDH1A1MAPTNPSR1SMN1; SMN2RAB9A
	SCHEMBL4684022	0.88	KMT2A (0.63)	ALDH1A1MAPTNPSR1SMN1; SMN2RAB9A
	SCHEMBL4683927	0.86	HSP90AA1 (0.59)	ALDH1A1MAPTNPSR1SMN1; SMN2RAB9A
	SCHEMBL4738582	0.83	MEN1 (0.58)	ALDH1A1MAPTNPSR1RAB9ANPC1
	SCHEMBL6649296	0.83	MEN1 (0.58)	ALDH1A1MAPTNPSR1RAB9ANPC1
	SCHEMBL4682689	0.83	ABCC9 (0.67)	ALDH1A1MAPTSMN1; SMN2RAB9ANPC1
	SCHEMBL4679775	0.82	LMNA (0.53)	ALDH1A1MAPTNPSR1SMN1; SMN2MEN1
	SCHEMBL6672512	0.82	LMNA (0.53)	ALDH1A1MAPTNPSR1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.