Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011871 | 0.91 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL2003926 | 0.88 | CNR1 (0.40) | LMNACNR1 | |
| SCHEMBL2007974 | 0.82 | HSD11B1 (0.43) | HSD11B1CNR1 | |
| SCHEMBL4685105 | 0.82 | HSD11B1 (0.43) | HSD11B1CNR1 | |
| SCHEMBL2008890 | 0.79 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL2010784 | 0.78 | ACHE (0.41) | HSD11B1CNR1 | |
| SCHEMBL2007089 | 0.78 | ALDH1A1 (0.42) | HSD11B1LMNACNR1 | |
| SCHEMBL8239514 | 0.77 | USP2 (0.40) | HSD11B1CNR1 | |
| SCHEMBL3135656 | 0.77 | GBA1 (0.43) | HSD11B1LMNA | |
| SCHEMBL3055583 | 0.77 | CNR1 (0.41) | HSD11B1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981504-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | NV Remynd (BE) | 2008-10-22 | — | — | EP | claimed |
| WO-2007090617-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | NV REMYND (BE) | 2007-08-16 | — | — | WO | claimed |