Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677777 | 0.89 | NPBWR1 (0.33) | P2RX7COMTNPBWR1 | |
| SCHEMBL4677636 | 0.89 | NPC1 (0.32) | P2RX7COMTNPBWR1 | |
| SCHEMBL4678151 | 0.81 | COMT (0.40) | P2RX7COMTNPBWR1 | |
| SCHEMBL31448215 | 0.81 | NOTUM (0.37) | COMT | |
| SCHEMBL4681846 | 0.81 | NOTUM (0.37) | COMT | |
| SCHEMBL4681813 | 0.80 | GAA (0.33) | COMT | |
| SCHEMBL4677931 | 0.80 | CCR1 (0.33) | — | |
| SCHEMBL8570147 | 0.80 | GAA (0.33) | COMTNPBWR1 | |
| SCHEMBL4679224 | 0.80 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL14303096 | 0.80 | PPOX (0.38) | COMTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |