Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678988 | 0.87 | NPBWR1 (0.33) | P2RX7GAAATMALDH1A1KMT2A | |
| SCHEMBL4681745 | 0.86 | MEN1 (0.37) | GAAATMALDH1A1KMT2AMAPT | |
| SCHEMBL5388413 | 0.80 | GAA (0.37) | GAAATMALDH1A1KMT2APLAU | |
| SCHEMBL4685244 | 0.80 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL31448207 | 0.79 | SORT1 (0.37) | GAAATMKMT2APLAUMAPT | |
| SCHEMBL4062616 | 0.79 | SORT1 (0.37) | GAAATMKMT2APLAUMAPT | |
| SCHEMBL4679229 | 0.78 | GAA (0.38) | GAAATMALDH1A1KMT2APLAU | |
| SCHEMBL4683040 | 0.78 | GAA (0.34) | GAAATMALDH1A1KMT2AKDM4E | |
| SCHEMBL27520995 | 0.74 | GAA (0.37) | GAAATMALDH1A1KMT2AKDM4E | |
| SCHEMBL6794821 | 0.74 | PPOX (0.44) | GAAATMALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |