SCHEMBL468545

SCHEMBL468545

CCCCCCCCC1(CCCCCCCC)C(=O)NC(=O)NC1=O

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 13/20 0.67
MMP2 P08253 12/20 0.67
MMP8 P22894 9/20 0.67
MMP13 P45452 9/20 0.67
MMP3 P08254 3/20 0.54
LMNA P02545 1/20 0.54
MEN1 O00255 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CRHBP P24387 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
CRHR2 Q13324 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5450754 1.00 MMP9 (0.67) MMP9MMP2MMP8MMP13MMP3
SCHEMBL712742 0.92 MMP9 (0.63) MMP9MMP2MMP8MMP13MMP3
SCHEMBL4390355 0.92 MMP9 (0.63) MMP9MMP2MMP8MMP13MMP3
SCHEMBL4379822 0.92 MMP9 (0.63) MMP9MMP2MMP8MMP13MMP3
SCHEMBL4382583 0.92 MMP9 (0.63) MMP9MMP2MMP8MMP13MMP3
SCHEMBL1683293 0.91 LMNA (0.58) MMP9MMP2MMP8MMP13MMP3
SCHEMBL1641551 0.90 MMP9 (0.61) MMP9MMP2MMP8MMP13MMP3
SCHEMBL918796 0.89 LMNA (0.64) MMP9MMP2MMP8MMP13MMP3
SCHEMBL6381385 0.84 MMP2 (0.59) MMP9MMP2MMP8MMP13MMP3
SCHEMBL27520073 0.84 MMP2 (0.59) MMP9MMP2MMP8MMP13MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2787043-B1 USE OF ORGANOGELATOR DERIVATIVES IN BITUMINOUS COMPOSITIONS TO IMPROVE THE RESISTANCE THEREOF TO CHEMICAL ATTACKS TOTAL MARKETING SERVICES (FR) 2018-03-21 EP disclosed
EP-2386606-B1 USE OF ORGANOGELATOR DERIVATIVES IN BITUMINOUS COMPOSITIONS TO IMPROVE THE RESISTANCE THEREOF TO CHEMICAL ATTACKS TOTAL MARKETING SERVICES (FR) 2018-03-21 EP disclosed
EP-2106423-B1 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTAL MARKETING SERVICES (FR) 2017-08-30 EP disclosed
US-9238752-B2 Bituminous composition with thermoreversible properties TOTAL RAFFINAGE MARKETING (FR) 2016-01-19 US disclosed
CN-102892838-B Organic gelling agent derivative in bituminous composition in order to improve the purposes of bituminous composition to the tolerance of chemical erosion TOTAL RAFFINAGE MARKETING (FR) 2015-11-25 CN disclosed
US-9127162-B2 Use of organogelator derivatives in bituminous compositions to improve the resistance of same to chemical stress TOTAL RAFFINAGE MARKETING (FR) 2015-09-08 US disclosed
EP-2787043-A1 Use of organogelling agents in bituminous compositions in order to improve the resistance thereof to chemical attacks TOTAL MARKETING SERVICES (FR) 2014-10-08 EP disclosed
US-20130298800-A1 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTALENERGIES ONETECH (FR) 2013-11-14 US disclosed
US-20130041075-A1 USE OF ORGANOGELATOR DERIVATIVES IN BITUMINOUS COMPOSITIONS TO IMPROVE THE RESISTANCE OF SAME TO CHEMICAL STRESS TOTAL RAFFINAGE MARKETING (FR) 2013-02-14 US disclosed
CN-102892838-A Use of organogelator derivatives in bituminous compositions to improve the resistance of same to chemical stress DREESSEN SY 2013-01-23 CN disclosed
EP-2386606-A1 Use of organogelling agents in bituminous compositions in order to improve the resistance thereof to chemical attacks Total Raffinage Marketing (FR) 2011-11-16 EP disclosed
WO-2011135549-A1 USE OF ORGANOGELATOR DERIVATIVES IN BITUMINOUS COMPOSITIONS TO IMPROVE THE RESISTANCE OF SAME TO CHEMICAL STRESS TOTAL RAFFINAGE MARKETING (FR) 2011-11-03 WO disclosed
US-8040768-B2 Information recording apparatus HITACHI, LTD. (JP) 2011-10-18 US disclosed
US-20100192804-A1 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTAL RAFFINAGE MARKETING (FR) 2010-08-05 US disclosed
EP-2106423-A2 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTAL RAFFINAGE MARKETING (FR) 2009-10-07 EP disclosed
WO-2008107551-A2 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTAL RAFFINAGE MARKETING (FR) 2008-09-12 WO disclosed