SCHEMBL1683293

SCHEMBL1683293

CCCCC1(CCCC)C(=O)NC(=O)NC1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
MMP9 P14780 7/20 0.56
MMP2 P08253 6/20 0.56
MMP13 P45452 5/20 0.56
MMP8 P22894 4/20 0.56
CYP3A4 P08684 2/20 0.45
MEN1 O00255 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CRHBP P24387 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
CRHR2 Q13324 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
MMP3 P08254 1/20 0.44
TP53 P04637 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468545 0.91 MMP9 (0.67) LMNAMMP9MMP2MMP13MMP8
SCHEMBL5450754 0.91 MMP9 (0.67) LMNAMMP9MMP2MMP13MMP8
Butethal SCHEMBL44262 0.91 LMNA (0.67) LMNAMMP9MMP2MMP13MMP8
SCHEMBL11109611 0.90 MMP9 (0.49) LMNAMMP9MMP2MMP13MMP8
Butethal SCHEMBL2718536 0.89 LMNA (0.64) LMNAMMP9MMP2MMP13MMP8
SCHEMBL2887982 0.85 LMNA (0.64) LMNAMMP9MMP2MMP13MMP8
SCHEMBL918796 0.85 LMNA (0.64) LMNAMMP9MMP2MMP13MMP8
SCHEMBL712742 0.83 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4382583 0.83 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4379822 0.83 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-20210236411-A1 BLOCK COPOLYMER-CONTAINING INORGANIC PARTICLE DISPERSION FOR COSMETICS SHISEIDO COMPANY, LTD. (JP) 2021-08-05 US disclosed
US-20210236410-A1 HAIR COSMETIC COMPRISING BLOCK COPOLYMER SHISEIDO COMPANY, LTD. (JP) 2021-08-05 US disclosed
EP-3811924-A1 BLOCK COPOLYMER-CONTAINING INORGANIC PARTICLE DISPERSION FOR COSMETICS Shiseido Company, Ltd. (JP) 2021-04-28 EP disclosed
EP-3804691-A1 HAIR COSMETIC COMPRISING BLOCK COPOLYMER Shiseido Company, Ltd. (JP) 2021-04-14 EP disclosed
CN-112203635-A Inorganic particle dispersion liquid for cosmetic containing block copolymer 株式会社资生堂 2021-01-08 CN disclosed
CN-112203636-A Hair cosmetic comprising block copolymer 株式会社资生堂 2021-01-08 CN disclosed
EP-2311920-B1 PIGMENT DISPERSIONS, BLOCK POLYMERS AND MANUFACTURING METHOD THEREFOR DAINICHISEIKA COLOR CHEM (JP) 2016-10-12 EP disclosed
US-8822591-B2 Pigment dispersions DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2014-09-02 US disclosed
US-20110136965-A1 PIGMENT DISPERSIONS, BLOCK POLYMERS AND MANUFACTURING METHOD THEREFOR DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2011-06-09 US disclosed
EP-2311920-A1 PIGMENT DISPERSIONS, BLOCK POLYMERS AND MANUFACTURING METHOD THEREFOR Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2011-04-20 EP disclosed
US-20050262647-A1 Agent for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-12-01 US disclosed
US-5456904-A Sunscreens; sunblocks; antiinflammatories THE PROCTER & GAMBLE COMPANY (US) 1995-10-10 US disclosed
WO-1995000112-A1 PHOTOPROTECTION COMPOSITIONS COMPRISING CERTAIN CHELATING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 LMNA 459/4885MMP9 3661/4885MMP2 1459/4885
US-20210236411-A1 BLOCK COPOLYMER-CONTAINING INORGANIC PARTICLE DISPERSION FOR COSMETICS H1-0, H1-4, H1-2 LMNA 3563/4885MMP9 3004/4885MMP2 3813/4885
US-20210236410-A1 HAIR COSMETIC COMPRISING BLOCK COPOLYMER DNMT1, H1-0, H1-5 LMNA 3888/4885MMP9 458/4885MMP2 975/4885
US-20050262647-A1 Agent for dyeing fibers containing keratin KRT18, CKAP4, KRTCAP2 LMNA 365/4885MMP9 4222/4885MMP2 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.