Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263267 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL15830721 | 0.79 | TSHR (0.46) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL1545421 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL4166359 | 0.77 | MAPT (0.44) | ALDH1A1TDP1TSHRCYP3A4KDM4E | |
| SCHEMBL563719 | 0.76 | GPR35 (0.46) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL5360919 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL2571514 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL4427648 | 0.73 | ALDH1A1 (0.71) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL27257326 | 0.72 | — | — | |
| SCHEMBL6537796 | 0.72 | CCR8 (0.53) | ALDH1A1TDP1TSHRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218211-A | A kind of simple and convenient process for preparing of nevirapine | 新发药业有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-118754847-A | Convenient synthesis method of N-alkyl substituted pyridone compound | 南通大学 | 2024-10-11 | — | — | CN | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| CN-112313231-B | OGA inhibitor compounds | 詹森药业有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-112313212-B | OGA inhibitor compounds | 詹森药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-3810608-B1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2022-08-10 | — | — | EP | disclosed |
| CN-105793254-B | Azaquinazoline carboxamide derivatives | 默克专利有限公司 | 2020-10-23 | — | — | CN | disclosed |
| EP-2925747-B1 | AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-06-24 | — | — | EP | disclosed |
| CN-110218211-B | Simple preparation method of nevirapine | 新发药业有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-110218211-B | Simple preparation method of nevirapine | 新发药业有限公司 | 2020-06-23 | — | — | CN | disclosed |
| US-5656634-A | N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1996018644-A9 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | — | 1996-08-01 | — | — | WO | disclosed |
| WO-1996018644-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1996-06-20 | — | — | WO | disclosed |
| US-5362878-A | Intermediates for making N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0609960-A1 | New N-heteroarylamide derivatives as inhibitors of acyl coenzyme A: cholestrol acyl transferase | PFIZER INC. (US) | 1994-08-10 | — | — | EP | disclosed |
| WO-1991004027-A1 | NEW N-ARYL AND N-HETEROARYLAMIDE AND UREA DERIVATIVES AS INHIBITORS OF ACYL COENZYME A: CHOLESTEROL ACYL TRANSFERASE (ACAT) | PFIZER INC. (US) | 1991-04-04 | — | — | WO | disclosed |
| CN-1050183-A | New N-aryl and N-heteroaryl amide and urea derivatives as acyl-coenzyme a cholesterol acyltransferase (ACAT) inhibitor | PFIZER (US) | 1991-03-27 | — | — | CN | disclosed |
| EP-0418071-A2 | New N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase | PFIZER INC. (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4131677-A | Anti-inflammatory oxazolo [5,4-b]pyridines | MERCK & CO., INC. (US) | 1978-12-26 | — | — | US | disclosed |
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALDH1A1 1863/4885TDP1 1942/4885TSHR 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.