Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPY2R | P49146 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901086 | 0.91 | CHRM1 (0.40) | CHRM1CHRM5CHRM3GRM4KMT2A | |
| SCHEMBL4684270 | 0.83 | AVPR2 (0.41) | CHRM1CHRM5CHRM3GRM4KMT2A | |
| SCHEMBL4743947 | 0.82 | GRM4 (0.39) | CHRM1CHRM5CHRM3GRM4KMT2A | |
| SCHEMBL8635111 | 0.82 | CHRM5 (0.41) | CHRM1CHRM5CHRM3MALT1GRM4 | |
| SCHEMBL7334875 | 0.75 | GRM4 (0.45) | CHRM1GRM4KMT2AKDM4EALDH1A1 | |
| SCHEMBL9087946 | 0.74 | FNTA (0.38) | KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL4684937 | 0.74 | AVPR2 (0.50) | CHRM1CHRM5CHRM3GRM4HTR1A | |
| SCHEMBL8634459 | 0.74 | CHRM5 (0.40) | CHRM1CHRM5CHRM3GRM4KMT2A | |
| SCHEMBL4685757 | 0.73 | MAPT (0.42) | CHRM1CHRM5CHRM3GRM4KMT2A | |
| SCHEMBL4684933 | 0.73 | AVPR2 (0.51) | CHRM1CHRM5CHRM3KMT2ANPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |