Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6261375 | 1.00 | CES2 (0.50) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL8107130 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27538125 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27505734 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL8103185 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27548987 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL8093379 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL1987108 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL21049873 | 0.98 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2374459 | 0.94 | CES2 (0.55) | CES2TSHRGPR84ALDH1A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129779-B2 | Thickening system in a percarbonate-containing blonding agent | Henkel IP & Holding GmbH (DE) | 2021-09-28 | — | — | US | claimed |
| US-11052027-B2 | Use of sodium chloride in bleaching agents based on percarbonate for human hair application | HENKEL AG & CO. KGAA (DE) | 2021-07-06 | — | — | US | claimed |
| US-20200206100-A1 | THICKENING SYSTEM IN A PERCARBONATE-CONTAINING BLONDING AGENT | HENKEL AG & CO. KGAA (DE) | 2020-07-02 | — | — | US | claimed |
| US-20200206104-A1 | USE OF SODIUM CHLORIDE IN BLEACHING AGENTS BASED ON PRECARBONATE FOR HUMAN HAIR APPLICATION | HENKEL AG & CO. KGAA (DE) | 2020-07-02 | — | — | US | claimed |
| US-10159854-B2 | Composition for altering the color of keratin fibers | L'OREAL (FR) | 2018-12-25 | — | — | US | claimed |
| US-20170266104-A1 | COMPOSITION FOR ALTERING THE COLOR OF KERATIN FIBERS | L'OREAL (FR) | 2017-09-21 | — | — | US | claimed |
| US-9642783-B2 | Depilatory compositions | L'OREAL (FR) | 2017-05-09 | — | — | US | claimed |
| EP-2579722-B1 | SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS | NEUDORFF W GMBH KG (DE) | 2016-11-23 | — | — | EP | claimed |
| EP-1489909-B1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | NEUDORFF W GMBH KG (DE) | 2016-11-02 | — | — | EP | claimed |
| US-20150283041-A1 | COMPOSITIONS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2015-10-08 | — | — | US | claimed |
| US-6509284-B1 | Thermoplastic substrate layer treated with a surfactant-modified odor control agent produced by chemically reacting a surfactant-producing compound with an odor control chelating agent | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-01-21 | — | — | US | claimed |
| EP-1261312-A2 | HAIR RELAXER COMPOSITIONS UTILIZING COMPLEXING AGENT ACTIVATORS | L'OREAL, S.A. (FR) | 2002-12-04 | — | — | EP | claimed |
| US-20020159962-A1 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL S.A. (FR) | 2002-10-31 | — | — | US | claimed |
| CN-1376075-A | Layer materials treated with surfactant-modified chelating agents | KIMBERLY CLARK CO (US) | 2002-10-23 | — | — | CN | claimed |
| WO-2002067875-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME | L'OREAL S.A. (FR) | 2002-09-06 | — | — | WO | claimed |
| US-6435193-B1 | STRAIGHTENING HAIR BY LANTHIONIZING KERATIN FIBERS; FORMING HYDROXIDE IONS IN SITU IN IONIZING SOLVENT FROM MULTIVALENT METAL HYDROXIDE AND ACTIVATOR; DOES NOT LEAVE RESIDUE THAT CAUSES ASHING OR WHITENING | L'OREAL S.A. (FR) | 2002-08-20 | — | — | US | claimed |
| WO-2002058651-A1 | HAIR RELAXER COMPOSITIONS UTILIZING CATION EXCHANGE COMPOSITIONS | L'OREAL S.A. (FR) | 2002-08-01 | — | — | WO | claimed |
| EP-1154806-A1 | LAYER MATERIALS TREATED WITH SURFACTANT-MODIFIED CHELATING AGENTS | Kimberly-Clark Worldwide, Inc. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2001064171-A2 | HAIR RELAXER COMPOSITIONS UTILIZING COMPLEXING AGENT ACTIVATORS | L'OREAL S.A. (FR) | 2001-09-07 | — | — | WO | claimed |
| WO-2000050098-A1 | LAYER MATERIALS TREATED WITH SURFACTANT-MODIFIED CHELATING AGENTS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-08-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129779-B2 | Thickening system in a percarbonate-containing blonding agent | KRT18, DSG1, POLR1C | ESR1 4343/4885CES2 4446/4885PPARG 1293/4885 |
| US-20200206100-A1 | THICKENING SYSTEM IN A PERCARBONATE-CONTAINING BLONDING AGENT | KRT18, DSG1, POLR1C | ESR1 4343/4885CES2 4446/4885PPARG 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.