Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.34 |
| ▸ | CSK | P41240 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 2/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202634 | 0.81 | KDR (0.50) | SRCKDRCSKTEKEPHB4 | |
| Hydrochloric Acid SCHEMBL5214533 | 0.72 | SRC (0.69) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL1012610 | 0.71 | ALDH1A1 (0.65) | KDRMKNK1EHMT2EHMT1KDM4E | |
| SCHEMBL3204423 | 0.68 | KDR (0.49) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL3201199 | 0.68 | SRC (0.51) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL3195370 | 0.64 | SRC (0.63) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL3206699 | 0.64 | SRC (0.74) | SRCKDRCSKTEK | |
| SCHEMBL1145699 | 0.64 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL13534270 | 0.62 | MTNR1A (0.50) | TDP1KDM4EALDH1A1 | |
| SCHEMBL27836799 | 0.61 | MKNK1 (0.39) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381599-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-09-24 | — | — | EP | claimed |