Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152061 | 0.87 | THRA (0.49) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL5150162 | 0.86 | MAPK1 (0.51) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL4234256 | 0.86 | MAPK1 (0.56) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL5151677 | 0.85 | NPY5R (0.48) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL5150280 | 0.84 | PNLIP (0.46) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL5149654 | 0.84 | PNLIP (0.52) | MAPK1NPY5RPKMMEN1KMT2A | |
| SCHEMBL5181103 | 0.83 | CYP2C9 (0.55) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL5183364 | 0.83 | MAPK1 (0.50) | MAPK1NPY5RCYP2C9CYP2C19MMP2 | |
| SCHEMBL13449739 | 0.82 | CA12 (0.70) | CYP2C9CYP2C19ALDH1A1CA12CA1 | |
| SCHEMBL9813659 | 0.82 | ALDH1A1 (0.60) | MAPK1CYP2C9CYP2C19HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |