Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 9/20 | 0.52 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181890 | 0.88 | PNLIP (0.55) | PNLIPGCGRPARGMAPTNPSR1 | |
| SCHEMBL5151677 | 0.86 | NPY5R (0.48) | MAPTNPSR1MEN1KMT2ANPY5R | |
| SCHEMBL5150280 | 0.85 | PNLIP (0.46) | PNLIPMAPTMEN1KMT2ANPY5R | |
| SCHEMBL4687744 | 0.84 | MAPK1 (0.61) | MAPTNPSR1MEN1PKMKMT2A | |
| SCHEMBL5151769 | 0.82 | PLA2G7 (0.49) | MAPTNPSR1MEN1PKMKMT2A | |
| SCHEMBL11207338 | 0.82 | PNLIP (0.61) | PNLIPPARGMAPTNPSR1STK39 | |
| SCHEMBL5169607 | 0.81 | TBXA2R (0.50) | NPY5RMAPK1 | |
| SCHEMBL5148241 | 0.80 | KCNJ6 (0.54) | MEN1KMT2AMAPK1 | |
| SCHEMBL11008397 | 0.79 | PNLIP (0.69) | PNLIPGCGRMAPTNPSR1MEN1 | |
| SCHEMBL5152061 | 0.79 | THRA (0.49) | MAPTMEN1KMT2ANPY5RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |