SCHEMBL468840

SCHEMBL468840

COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.71
MEN1 O00255 4/20 0.71
HCRTR1 O43613 1/20 0.71
TACR1 P25103 5/20 0.71
MAPT P10636 3/20 0.66
TP53 P04637 2/20 0.66
KDM4E B2RXH2 1/20 0.66
ALDH1A1 P00352 1/20 0.66
LMNA P02545 1/20 0.66
CYP1A2 P05177 1/20 0.66
POLB P06746 1/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2D6 P10635 1/20 0.66
CYP2C9 P11712 1/20 0.66
NFKB1 P19838 1/20 0.66
APEX1 P27695 1/20 0.66
CYP2C19 P33261 1/20 0.66
THPO P40225 1/20 0.66
BLM P54132 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3184939 1.00 KMT2A (0.71) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL29401459 1.00 KMT2A (0.71) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL29138492 0.90 TACR1 (0.63) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL16626132 0.90 TACR1 (0.63) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL6362124 0.90 TACR1 (0.63) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL6355051 0.90 TACR1 (0.63) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL850315 0.90 TACR1 (0.74) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL3185689 0.90 TACR1 (0.74) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL5385762 0.90 TACR1 (0.72) KMT2AMEN1HCRTR1TACR1MAPT
SCHEMBL30359404 0.90 TACR1 (0.72) KMT2AMEN1HCRTR1TACR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2026-04-16 US claimed
EP-4345104-B1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-08-28 EP claimed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 WO claimed
EP-4345104-A1 METHOD FOR PREPARING LIRAGLUTIDE Bachem Holding AG (CH) 2024-04-03 EP claimed
EP-1428537-B1 STABILIZED PREPARATIONS CONTAINING ANTIBODY CHUGAI PHARMACEUTICAL CO LTD (JP) 2008-11-19 EP claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2026-04-16 US disclosed
US-12486300-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-12-02 US disclosed
US-12419861-B2 Method for preventing and/or treating chronic traumatic encephalopathy-i EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) 2025-09-23 US disclosed
US-20240316223-A1 Oxidative Cyclization Reagents for Chemoselective Tryptophan Bioconjugation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-09-26 US disclosed
EP-4345104-B1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-08-28 EP disclosed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 WO disclosed
EP-4345104-A1 METHOD FOR PREPARING LIRAGLUTIDE Bachem Holding AG (CH) 2024-04-03 EP disclosed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US disclosed
EP-1260230-A1 PREPARATIONS STABILIZED OVER LONG TIME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-11-27 EP disclosed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP disclosed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO disclosed
US-4761233-A Novel membranes and process for making them MEMBRANE PRODUCTS KIRYAT WEIZMANN LTD. (IL) 1988-08-02 US disclosed
EP-0238276-A2 Novel membranes and process for making them MEMBRANE PRODUCTS KIRYAT WEIZMANN LTD. (IL) 1987-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486300-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity TFAM, HSPE1, PRDX3 KMT2A 696/4885MEN1 153/4885HCRTR1 3348/4885
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE GLP1R, IAPP, VIP KMT2A 2447/4885MEN1 610/4885HCRTR1 1502/4885
US-20240316223-A1 Oxidative Cyclization Reagents for Chemoselective Tryptophan Bioconjugation TDO2, TPH1, TPH2 KMT2A 2305/4885MEN1 3689/4885HCRTR1 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.