SCHEMBL468911

SCHEMBL468911

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nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.67
▸ MAPT P10636 1/20 0.54
▸ MEN1 O00255 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ FOLH1 Q04609 6/20 0.47
▸ GRN P28799 2/20 0.46
▸ SORT1 Q99523 2/20 0.46
▸ MME P08473 1/20 0.46
▸ LAP3 P28838 3/20 0.45
▸ NAALAD2 Q9Y3Q0 2/20 0.43
▸ PLA2G2A P14555 2/20 0.43
▸ PLA2G5 P39877 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468910 1.00 ALDH1A1 (0.67) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL14436768 0.84 ALDH1A1 (0.55) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL15757059 0.83 ALDH1A1 (0.53) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL19545981 0.83 MMP1 (0.53) ALDH1A1MAPT
SCHEMBL8017457 0.83 ALDH1A1 (0.53) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL19967700 0.83 ALDH1A1 (0.53) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL26079410 0.81 ALDH1A1 (0.60) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL865121 0.81 TGFBR1 (0.52) ALDH1A1MAPTFOLH1MMENAALAD2
SCHEMBL865120 0.81 TGFBR1 (0.52) ALDH1A1MAPTFOLH1MMENAALAD2
SCHEMBL29590916 0.81 ALDH1A1 (0.51) ALDH1A1MAPTMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2311452-B2 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2020-12-30 — — EP disclosed
EP-2311452-B9 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2014-12-24 — — EP disclosed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 — — US disclosed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 — — US disclosed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 — — US disclosed
EP-2311452-A1 Topical composition comprising n-acetyl glucosamine Yu, Ruey J. (US) 2011-04-20 — — EP disclosed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 — — US disclosed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 — — US disclosed
EP-2080504-A2 Topical composition comprising n-acetylaldosamines or n-acetylamino acids Yu, Ruey J. (US) 2009-07-22 — — EP disclosed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 — — EP disclosed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 — — EP disclosed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 — — US disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 — — WO disclosed
US-5543397-A New N-acyl dipeptides and their use DEGUSSA AKTIENGESELLSCHAFT (DE) 1996-08-06 — — US disclosed
US-5534538-A N-acyl dipeptides and their compositions DEGUSSA AKTIENGESELLSCHAFT (DE) 1996-07-09 — — US disclosed
EP-0466030-B1 N-acyl dipeptides and their use DEGUSSA (DE) 1995-10-11 — — EP disclosed
EP-0466030-A2 N-acyl dipeptides and their use DEGUSSA AG (DE) 1992-01-15 — — EP disclosed
EP-0050196-B1 PROCESS FOR THE PREPARATION OF PEPTIDES Degussa Aktiengesellschaft (DE) 1983-11-23 — — EP disclosed
US-4374062-A ASSYMETRICAL HYDROGENATION OF DEHYDROPEPTIDES USING A PHODIUM COMPLEX CATALYST DEGUSSA AKTIENGESELLSCHAFT (DE) 1983-02-15 — — US disclosed
EP-0050196-A1 Process for the preparation of peptides Degussa Aktiengesellschaft (DE) 1982-04-28 — — EP disclosed
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