Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694392 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL4690928 | 0.74 | — | — | |
| SCHEMBL10432656 | 0.73 | PSMB8 (0.36) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL2308024 | 0.73 | CYP19A1 (0.40) | ALDH1A1 | |
| SCHEMBL31719750 | 0.70 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1PDCD1CD274 | |
| SCHEMBL6219249 | 0.70 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1PDCD1CD274 | |
| SCHEMBL3966265 | 0.69 | FAAH (0.34) | GABRA1GABRB2TSHR | |
| SCHEMBL3966479 | 0.69 | CA2 (0.34) | GABRA1GABRB2 | |
| SCHEMBL3962976 | 0.69 | FAAH (0.34) | GABRA1GABRB2TSHR | |
| SCHEMBL3964352 | 0.69 | EDNRA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |