Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689929 | 0.76 | GABRA1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL10432656 | 0.72 | PSMB8 (0.36) | GABRA1GABRB2 | |
| SCHEMBL4619300 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2 | |
| SCHEMBL4690679 | 0.69 | GABRA1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL3962564 | 0.68 | PDE10A (0.41) | — | |
| SCHEMBL1701340 | 0.67 | GABRA1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL1759301 | 0.67 | PARP1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL4690928 | 0.67 | — | — | |
| SCHEMBL3962703 | 0.67 | CA2 (0.41) | GABRA1GABRB2 | |
| SCHEMBL13263824 | 0.66 | GABRA1 (0.43) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |