Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469283 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAMEN1ALOX15 | |
| SCHEMBL9469385 | 0.90 | GAA (0.39) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470368 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470503 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470300 | 0.87 | MAPT (0.39) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470466 | 0.82 | KMT2A (0.47) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9469535 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470341 | 0.78 | MEN1 (0.40) | ALDH1A1MAPTGAAMEN1ALOX15 | |
| SCHEMBL9470196 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9470115 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399155-B1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2008-05-28 | — | — | EP | disclosed |
| US-6414153-B1 | TREATMENT OF INFLAMMATORY OR IMMUNE CELL-MEDIATED DISEASE OR CONDITION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |