Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 11/20 | 0.46 |
| ▸ | CCL5 | P13501 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692822 | 0.89 | SMYD3 (0.46) | CCR5CCL5ALDH1A1 | |
| SCHEMBL4690462 | 0.88 | MEN1 (0.46) | CCR5CCL5ALDH1A1 | |
| Cyclopentane SCHEMBL4694432 | 0.85 | CCR5 (0.58) | CCR5 | |
| SCHEMBL4690501 | 0.83 | TSHR (0.49) | CCR5CCL5ALDH1A1TSHR | |
| SCHEMBL4693123 | 0.81 | CCR5 (0.50) | CCR5CCL5ALDH1A1 | |
| SCHEMBL4696493 | 0.80 | CCR5 (0.59) | CCR5CCL5 | |
| SCHEMBL4694458 | 0.80 | CCR5 (0.53) | CCR5CCL5 | |
| SCHEMBL4694095 | 0.79 | CCR5 (0.51) | CCR5CCL5 | |
| SCHEMBL3290682 | 0.79 | CCR5 (0.70) | CCR5CCL5 | |
| SCHEMBL3285413 | 0.79 | CCR5 (0.70) | CCR5CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |