Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9957339 | 0.98 | KCNN4 (0.61) | KCNN4TAAR1MAPK1DPP4NR3C2 | |
| Bromide SCHEMBL28232025 | 0.98 | KCNN4 (0.61) | KCNN4TAAR1MAPK1DPP4NR3C2 | |
| SCHEMBL6891739 | 0.82 | KCNN4 (0.48) | KCNN4TAAR1MAPK1DPP4NR3C2 | |
| Bromide SCHEMBL28188129 | 0.81 | KCNN4 (0.44) | KCNN4DPP4CYP2C19HIF1AALDH1A1 | |
| SCHEMBL19153594 | 0.81 | TSHR (0.44) | KCNN4MAPK1KIF11ALDH1A1ALOX15 | |
| SCHEMBL28798433 | 0.81 | KCNN4 (0.64) | KCNN4TAAR1MAPK1NR3C2KIF11 | |
| SCHEMBL22430335 | 0.79 | TSHR (0.48) | KCNN4KIF11CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL13900473 | 0.79 | KCNN4 (0.45) | KCNN4TAAR1MAPK1DPP4KIF11 | |
| SCHEMBL11922815 | 0.79 | KCNN4 (0.45) | KCNN4TAAR1KIF11ALDH1A1HDAC3 | |
| SCHEMBL2490805 | 0.78 | KCNN4 (1.00) | KCNN4TAAR1MAPK1NR3C2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255428-A1 | AROMATIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOSITION, AND METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT | 三菱ケミカル株式会社 | 2022-12-08 | — | — | WO | disclosed |
| CN-114981366-A | Hydrophobic, low glass transition temperature oligomers with high levels of chain transfer agents | 本杰明·摩尔公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11384090-B2 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
| US-20190088889-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2019-03-21 | — | — | US | disclosed |
| WO-2017205041-A1 | HIGH CHARGE DENSITY METALLOPHOSPHATE MOLECULAR SIEVES | UOP LLC (US) | 2017-11-30 | — | — | WO | disclosed |
| CN-105592892-A | Compositions comprising gallates and gallamides | COLGATE PALMOLIVE CO | 2016-05-18 | — | — | CN | disclosed |
| WO-2015050505-A1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-04-09 | — | — | WO | disclosed |
| EP-2594554-A1 | BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20130116227-A1 | BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-05-09 | — | — | US | disclosed |
| US-20120064181-A1 | P2X3 Receptor Antagonists for Treatment of Pain | MERCK SHARP & DOHME LLC | 2012-03-15 | — | — | US | disclosed |
| US-20120046283-A1 | COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS | AFRAXIS INC. (US) | 2012-02-23 | — | — | US | disclosed |
| US-7354946-B2 | prominent growth inhibitory activity against tumor cells; cyclin dependent kinase inhibitors; colon cancer; N'-(3-t-butylisoindolino[3,2-b]oxazolidin-4-on-8-yl)-N-(4-(N-benzylpyrrolidin-3-yl)pyridin-2-yl)urea | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| US-7354946-B2 | prominent growth inhibitory activity against tumor cells; cyclin dependent kinase inhibitors; colon cancer; N'-(3-t-butylisoindolino[3,2-b]oxazolidin-4-on-8-yl)-N-(4-(N-benzylpyrrolidin-3-yl)pyridin-2-yl)urea | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| US-20070027147-A1 | Biarylurea derivatives | MSD K.K. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-20070027147-A1 | Biarylurea derivatives | MSD K.K. (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-0094191-B1 | ANTIULCER 2-GUANIDINO-4-(2-SUBSTITUTED-AMINO-4-IMIDAZOLYL)-THIAZOLES AND PROCESS THEREFOR | PFIZER INC. (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4435396-A | FROM 2-AMINO-5-ACETYLOXAZOLE | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0094191-A1 | Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)-thiazoles and process therefor | PFIZER INC. (US) | 1983-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116227-A1 | BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | MC2R, NR3C2, REN | KCNN4 835/4885TAAR1 356/4885MAPK1 1920/4885 |
| US-11384090-B2 | Spiropyrrolidine derived antiviral agents | ACE, ACE2, REN | KCNN4 140/4885TAAR1 2860/4885MAPK1 1006/4885 |
| US-20070027147-A1 | Biarylurea derivatives | CDK6, CDK4, CCNI | KCNN4 3973/4885TAAR1 3305/4885MAPK1 1152/4885 |
| US-20120064181-A1 | P2X3 Receptor Antagonists for Treatment of Pain | P2RX3, P2RX1, P2RX2 | KCNN4 489/4885TAAR1 343/4885MAPK1 2759/4885 |
| US-20120046283-A1 | COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS | PAK2, PAK5, PAK6 | KCNN4 4260/4885TAAR1 1238/4885MAPK1 703/4885 |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, REN | KCNN4 194/4885TAAR1 3502/4885MAPK1 877/4885 |
| US-20190088889-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | TIMCC, ICOSLG, NUDT1 | KCNN4 19/4885TAAR1 612/4885MAPK1 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.