SCHEMBL4692915

SCHEMBL4692915

CN(C)c1ccc(/C=C/C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.75
CRHR2 Q13324 1/20 0.75
TLR9 Q9NR96 1/20 0.75
MAPT P10636 3/20 0.73
NPC1 O15118 2/20 0.72
KMT2A Q03164 2/20 0.72
CYP1B1 Q16678 2/20 0.72
CASP3 P42574 1/20 0.72
RAB9A P51151 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
SENP8 Q96LD8 1/20 0.72
SENP7 Q9BQF6 1/20 0.72
SENP6 Q9GZR1 1/20 0.72
MAOB P27338 10/20 0.69
MAOA P21397 3/20 0.69
CXCL12 P48061 1/20 0.67
MEN1 O00255 1/20 0.64
MAPK1 P28482 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4692916 1.00 CRHBP (0.75) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL11144499 1.00 CRHBP (0.75) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL2911444 0.92 TLR9 (0.87) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL2911445 0.92 TLR9 (0.87) CRHBPCRHR2TLR9MAPTNPC1
4',4-Dichlorochalcone SCHEMBL659210 0.87 MAOB (0.86) MAPTCYP1B1MAOBMAOACXCL12
4',4-Dichlorochalcone SCHEMBL659211 0.87 MAOB (0.86) MAPTCYP1B1MAOBMAOACXCL12
SCHEMBL25200425 0.86 CRHBP (1.00) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL25205299 0.86 MAPT (0.79) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL5950050 0.86 MAPT (0.77) CRHBPCRHR2TLR9MAPTNPC1
SCHEMBL25200423 0.86 CRHBP (1.00) CRHBPCRHR2TLR9MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312456-B1 Acrylate/chalcone polystyrene composite and uses thereof IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-05-27 US disclosed
US-12187875-B1 Polystyrene-based chalcone, method of preparation, and uses thereof IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-01-07 US disclosed
US-8754179-B2 Light activated shape memory co-polymers CORNERSTONE RESEARCH GROUP, INC. (US) 2014-06-17 US disclosed
US-20080021166-A1 Light Activated Shape Memory Co-Polymers GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2008-01-24 US disclosed
EP-1799771-A2 LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2007-06-27 EP disclosed
WO-2007001407-A2 LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2007-01-04 WO disclosed
US-4908447-A 2-,6-diphenylpyridine compounds useful as dye precursors BASF AKTIENGESELLSCHAFT (DE) 1990-03-13 US disclosed