Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 4/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699788 | 0.84 | KIF11 (0.44) | KIF11GPR84KMT2AKDM4EKEAP1 | |
| SCHEMBL699552 | 0.74 | TNKS2 (0.44) | KIF11MEN1KMT2AKDM4ETDO2 | |
| SCHEMBL546371 | 0.70 | CYP1A2 (0.42) | DAOKIF11MEN1KMT2AKDM4E | |
| SCHEMBL316411 | 0.67 | ALDH1A1 (0.41) | KIF11MEN1KMT2AKDM4EKEAP1 | |
| SCHEMBL209219 | 0.67 | DAO (0.48) | DAOCDK2GPR84MEN1KMT2A | |
| SCHEMBL1517851 | 0.66 | KIF11 (0.61) | DAOKIF11CCNB2CDK1CCNB1 | |
| SCHEMBL29507671 | 0.66 | KIF11 (0.61) | DAOKIF11CCNB2CDK1CCNB1 | |
| SCHEMBL23369904 | 0.65 | KIF11 (0.82) | DAOKIF11CCNB2CDK1CCNB1 | |
| SCHEMBL19481419 | 0.65 | AHR (0.52) | DAOKIF11CCNB2CDK1CCNB1 | |
| SCHEMBL4031293 | 0.65 | GPR84 (0.58) | GPR84TDO2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |