Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 6/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453317 | 0.87 | APP (0.56) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL453426 | 0.85 | APP (0.49) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL19889343 | 0.82 | MAPT (0.46) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL7079761 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTNPC1RAB9ATSHR | |
| SCHEMBL16034589 | 0.80 | APP (0.73) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL14093383 | 0.80 | TDP1 (0.58) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL13016959 | 0.79 | TDP1 (0.59) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL13016958 | 0.78 | MAPT (0.63) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL20876156 | 0.77 | SMN1; SMN2 (0.50) | APPSMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL6482287 | 0.77 | SYK (0.47) | SMN1; SMN2MAPTNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9377466-B2 | Compounds and methods | MODPRO AB (SE) | 2016-06-28 | — | — | US | disclosed |
| US-9377466-B2 | Compounds and methods | MODPRO AB (SE) | 2016-06-28 | — | — | US | disclosed |
| US-20130261013-A1 | Compounds and Methods | MODPRO AB (SE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261013-A1 | Compounds and Methods | MODPRO AB (SE) | 2013-10-03 | — | — | US | disclosed |
| WO-2012032068-A2 | COMPOUNDS AND METHODS | MODPRO AB (SE) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261013-A1 | Compounds and Methods | NOS2, NOS1, NOS3 | APP 1544/4885SMN1; SMN2 3681/4885MAPT 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.