Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694768 | 0.90 | HDAC1 (0.36) | SMN1; SMN2 | |
| SCHEMBL4696628 | 0.85 | HDAC1 (0.35) | SMN1; SMN2 | |
| SCHEMBL4692560 | 0.85 | CD274 (0.39) | KDM4E | |
| SCHEMBL4696335 | 0.85 | PDCD1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4691952 | 0.83 | PDCD1 (0.35) | OPRK1DPP4ALDH1A1OPRM1 | |
| SCHEMBL4695744 | 0.81 | HDAC1 (0.37) | RAB9AKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6027383 | 0.81 | OPRM1 (0.36) | OPRK1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4691194 | 0.81 | DRD4 (0.38) | RAB9AKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5272930 | 0.81 | SPHK2 (0.34) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4695736 | 0.80 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893577-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006138218-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-12-28 | — | — | WO | claimed |