Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 12/20 | 0.34 |
| ▸ | CCL5 | P13501 | 3/20 | 0.32 |
| ▸ | RBP4 | P02753 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694498 | 0.84 | CCR5 (0.37) | CCR5CCL5 | |
| SCHEMBL4695377 | 0.83 | CCR5 (0.37) | CCR5CCL5 | |
| SCHEMBL4694111 | 0.81 | KMT2A (0.34) | CCR5RBP4 | |
| SCHEMBL4695010 | 0.80 | KMT2A (0.38) | CCR5CCL5 | |
| SCHEMBL4692781 | 0.80 | PKM (0.36) | CCR5CCL5 | |
| SCHEMBL4692061 | 0.77 | CCR5 (0.37) | CCR5CCL5 | |
| SCHEMBL4694094 | 0.77 | CHRNB2 (0.44) | CCR5 | |
| SCHEMBL4694116 | 0.76 | HCRTR2 (0.38) | CCR5 | |
| SCHEMBL4695866 | 0.76 | CCR5 (0.36) | CCR5CCL5 | |
| SCHEMBL4693785 | 0.75 | CCR5 (0.32) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |