Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696289 | 0.83 | THRB (0.38) | TP53MALT1MAPTLMNAALDH1A1 | |
| SCHEMBL4695194 | 0.79 | TP53 (0.42) | TP53MALT1MAPTLMNAMEN1 | |
| SCHEMBL4695896 | 0.78 | POLB (0.46) | TP53MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4694793 | 0.77 | MAPT (0.43) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL3286924 | 0.74 | TP53 (0.53) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL4690604 | 0.71 | TP53 (0.44) | TP53MALT1MAPTLMNAMEN1 | |
| SCHEMBL4690539 | 0.70 | TP53 (0.45) | TP53MALT1MAPTLMNAMEN1 | |
| SCHEMBL4695171 | 0.69 | TP53 (0.40) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL3283676 | 0.68 | TP53 (0.53) | TP53MALT1MAPTLMNAMEN1 | |
| SCHEMBL5662686 | 0.68 | MALT1 (0.50) | TP53MALT1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |