Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185521 | 0.85 | HHAT (0.36) | HHAT | |
| SCHEMBL5260323 | 0.74 | ACE (0.42) | AGTR2 | |
| SCHEMBL4697074 | 0.73 | NPC1 (0.34) | AGTR2 | |
| SCHEMBL4696279 | 0.70 | AGTR2 (0.35) | AGTR2HTT | |
| SCHEMBL4695695 | 0.70 | GRIN1 (0.37) | — | |
| SCHEMBL4751291 | 0.67 | HHAT (0.38) | HHAT | |
| SCHEMBL5254424 | 0.67 | HTT (0.31) | HTT | |
| SCHEMBL3300139 | 0.65 | — | — | |
| SCHEMBL11612302 | 0.65 | NPC1 (0.33) | — | |
| SCHEMBL4751946 | 0.65 | HHAT (0.45) | HHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |