Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185349 | 0.83 | MMP2 (0.40) | POLB | |
| SCHEMBL5256022 | 0.81 | ACE (0.41) | ACEPOLBAGTR2EDNRA | |
| SCHEMBL4695695 | 0.81 | GRIN1 (0.37) | ACEGRIN1GRIN2BSIGMAR1 | |
| SCHEMBL4696326 | 0.74 | AGTR2 (0.33) | AGTR2 | |
| SCHEMBL4695496 | 0.74 | KEAP1 (0.45) | POLB | |
| SCHEMBL5023851 | 0.74 | ACE (0.66) | ACE | |
| SCHEMBL5254567 | 0.73 | ACE (0.36) | ACEPOLB | |
| SCHEMBL4695538 | 0.72 | — | — | |
| SCHEMBL5254943 | 0.71 | NPC1 (0.38) | ACE | |
| SCHEMBL16111164 | 0.71 | ACE (0.68) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |