Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.46 |
| ▸ | SPR | P35270 | 5/20 | 0.43 |
| ▸ | CCR1 | P32246 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229245 | 0.93 | SPR (0.44) | EIF4A3SPRCCR1NPC1RAB9A | |
| SCHEMBL5231927 | 0.79 | CYP2C9 (0.42) | RAB9AL3MBTL1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL5230484 | 0.79 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL5239352 | 0.78 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL5238002 | 0.78 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL4692413 | 0.77 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL5235906 | 0.77 | HCRTR1 (0.46) | KMT2AMEN1NPC1HCRTR1HCRTR2 | |
| SCHEMBL5231911 | 0.77 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL5238120 | 0.77 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL5233800 | 0.77 | KMT2A (0.37) | KMT2AHCRTR1HCRTR2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |