SCHEMBL469643

SCHEMBL469643

NCCCCCCOCCCCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.73
HTR2A P28223 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
IDO1 P14902 1/20 0.52
HRH1 P35367 4/20 0.50
CYP2A6 P11509 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
MAOB P27338 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9556361 0.98 MAOA (0.70) MAOAHTR2ATDP1L3MBTL1IDO1
SCHEMBL22268839 0.96 MAOA (0.67) MAOAHTR2ATDP1L3MBTL1IDO1
SCHEMBL10818930 0.94 MAOA (0.69) MAOAHTR2AIDO1CYP2A6SMN1; SMN2
SCHEMBL1579959 0.92 MAOA (0.61) MAOAHTR2ATDP1L3MBTL1IDO1
SCHEMBL29263651 0.90 MAOA (0.63) MAOAHTR2ATDP1L3MBTL1IDO1
SCHEMBL19472539 0.90 MAOA (0.63) MAOAHTR2AIDO1CYP2A6SMN1; SMN2
SCHEMBL7448881 0.90 TDP1 (0.61) MAOATDP1L3MBTL1IDO1SIGMAR1
SCHEMBL7449055 0.90 TDP1 (0.61) MAOATDP1L3MBTL1IDO1SIGMAR1
SCHEMBL7449325 0.90 TDP1 (0.61) MAOATDP1L3MBTL1IDO1SIGMAR1
SCHEMBL8048487 0.90 TDP1 (0.61) MAOATDP1L3MBTL1IDO1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101712622-B Method for preparing anti-asthmatic medicament of salmeterol UNIV ZHEJIANG WANLI 2012-10-03 CN claimed
CN-101712622-A Method for preparing anti-asthmatic medicament of salmeterol UNIV ZHEJIANG WANLI 2010-05-26 CN claimed
EP-1132373-B1 NEW DERIVATIVES OF 6-(4-PHENYLBUTOXY)HEXYLAMINE AND PROCESS FOR PRODUCING SALMETEROL VITA LAB (ES) 2003-11-19 EP claimed
US-6388134-B1 CHEMICAL INTERMEDIATES INKE, S.A. (ES) 2002-05-14 US claimed
EP-1132373-A2 NEW DERIVATIVES OF 6-(4-PHENYLBUTOXY)HEXYLAMINE AND PROCESS FOR PRODUCING SALMETEROL VITA-INVEST, S.A. (ES) 2001-09-12 EP claimed
US-20250319096-A1 METHODS AND COMPOUNDS FOR TREATING INFLAMMATION PANTHERICS INCORPERATED (US) 2025-10-16 US disclosed
EP-3570814-B1 MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS UNIV GENT (BE) 2023-11-29 EP disclosed
WO-2023059443-A1 METHODS AND COMPOUNDS FOR TREATING INFLAMMATION PANTHERICS INCORPORATED (US) 2023-04-13 WO disclosed
CN-105884625-A synthetic method of R-salmeterol 浙江工业大学 2016-08-24 CN disclosed
EP-1937626-B1 Process and intermediates for the preparation of Salmeterol GENERICS UK LTD (GB) 2016-02-17 EP disclosed
US-8648214-B2 Processes suitable for the preparation of salmeterol GENERICS [UK] LIMITED (GB) 2014-02-11 US disclosed
US-8648214-B2 Processes suitable for the preparation of salmeterol GENERICS [UK] LIMITED (GB) 2014-02-11 US disclosed
US-5243076-A Adrenergic stimulant intermediates GLAXO GROUP LTD. 1993-09-07 US disclosed
US-5236900-A Treating Candida infections SCHERING CORPORATION (US) 1993-08-17 US disclosed
US-5225445-A Respiratory system disorders GLAXO GROUP LTD. 1993-07-06 US disclosed
EP-0500853-A1 PHENYLETHANOLAMINES, DRUGS CONTAINING THESE COMPOUNDS, AND A METHOD OF PREPARING THEM. THOMAE GMBH DR K (DE) 1992-09-02 EP disclosed
US-5126375-A Asthma, chronic bronchitis GLAXO GROUP LTD. (GB) 1992-06-30 US disclosed
WO-1992004316-A1 PHENYLETHANOLAMINES, DRUGS CONTAINING THESE COMPOUNDS, AND A METHOD OF PREPARING THEM DR. KARL THOMAE GMBH (DE) 1992-03-19 WO disclosed
US-5091422-A Treating inflammatory or allergic skin disease, lowering gastric acidity GLAXO GROUP LIMITED (GB) 1992-02-25 US disclosed
US-4992474-A Adrenergic stimulants GLAXO GROUP LTD. (GB) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319096-A1 METHODS AND COMPOUNDS FOR TREATING INFLAMMATION MMP8, TNF, MPO MAOA 1728/4885HTR2A 3458/4885TDP1 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.