Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698358 | 0.97 | PRKCA (0.39) | DGKAMAPK1ALDH1A1PRKCAGAA | |
| SCHEMBL3109237 | 0.94 | DGKA (0.40) | DGKAMAPK1ALDH1A1PRKCAGAA | |
| SCHEMBL3101630 | 0.88 | DGKA (0.49) | DGKAMAPK1ALDH1A1PRKCAMAPT | |
| SCHEMBL4698375 | 0.88 | NAAA (0.43) | MAPK1ALDH1A1PRKCAGAALMNA | |
| SCHEMBL3459097 | 0.87 | DGKA (0.56) | DGKAMAPK1ALDH1A1PRKCAMAPT | |
| SCHEMBL13541624 | 0.86 | ALDH1A1 (0.42) | MAPK1ALDH1A1RECQLL3MBTL1LMNA | |
| SCHEMBL3109452 | 0.86 | DGKA (0.58) | DGKAALDH1A1PRKCAMAPTLMNA | |
| SCHEMBL4700272 | 0.85 | BRD4 (0.42) | DGKAL3MBTL1LMNA | |
| SCHEMBL4702471 | 0.85 | NAAA (0.47) | MAPK1ALDH1A1PRKCAGAAMAPT | |
| SCHEMBL2037671 | 0.84 | NAAA (0.42) | MAPK1ALDH1A1PRKCALMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |