Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004782 | 0.86 | MAPT (0.49) | ALDH1A1SMN1; SMN2CNR1GAAMAPK1 | |
| SCHEMBL4694766 | 0.76 | CNR1 (0.56) | SMN1; SMN2CNR1SRD5A1SRD5A2 | |
| SCHEMBL4696323 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CNR1ACHEPGR | |
| SCHEMBL11002262 | 0.73 | MAPT (0.48) | ALDH1A1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL11695674 | 0.71 | LMNA (0.55) | ALDH1A1SMN1; SMN2ACHEGAAMAPK1 | |
| SCHEMBL8728950 | 0.70 | CNR1 (0.63) | ALDH1A1CNR1MAPK1HSD17B10SRD5A1 | |
| SCHEMBL30257325 | 0.70 | CNR1 (0.63) | ALDH1A1CNR1MAPK1HSD17B10SRD5A1 | |
| Phenyl Methylcarbamate SCHEMBL78497 | 0.70 | CYP1A2 (0.57) | ALDH1A1SMN1; SMN2ACHEBCHEPGR | |
| SCHEMBL1690756 | 0.70 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2ACHEBCHEPGR | |
| SCHEMBL29682691 | 0.70 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2ACHEBCHEPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |