Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693418 | 0.78 | CNR1 (0.39) | GAACNR1 | |
| SCHEMBL4696940 | 0.75 | ALDH1A1 (0.47) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9040225 | 0.74 | CNR1 (0.42) | ALDH1A1CNR1 | |
| Bendiocarb SCHEMBL7533636 | 0.68 | ALDH1A1 (0.92) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL30989358 | 0.67 | ALDH1A1 (0.57) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL5191682 | 0.67 | ALDH1A1 (0.57) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL8285503 | 0.67 | TRPA1 (0.47) | ALDH1A1GAAHSD17B10LMNACNR1 | |
| SCHEMBL7168856 | 0.65 | ALDH1A1 (0.46) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Bendiocarb SCHEMBL3954562 | 0.65 | ALDH1A1 (1.00) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Bendiocarb SCHEMBL22080 | 0.65 | ALDH1A1 (1.00) | ALDH1A1PGRGAAPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |