Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 14/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253781 | 0.97 | POLB (0.40) | POLBGAANPSR1PRKCAENO1 | |
| SCHEMBL3106135 | 0.94 | POLB (0.42) | POLBGAANPSR1PRKCAENO1 | |
| SCHEMBL13748507 | 0.85 | ALOX12 (0.38) | PRKCAALOX12 | |
| SCHEMBL1949595 | 0.85 | ALOX12 (0.38) | PRKCAALOX12 | |
| SCHEMBL917159 | 0.84 | ENO1 (0.36) | POLBGAANPSR1PRKCAENO1 | |
| SCHEMBL1280224 | 0.84 | ALOX12 (0.37) | ALOX12 | |
| SCHEMBL2037671 | 0.83 | NAAA (0.42) | PRKCA | |
| SCHEMBL4696869 | 0.83 | ALDH1A1 (0.41) | GAAPRKCAALOX12 | |
| SCHEMBL28508420 | 0.82 | PPARA (0.40) | ALOX12CCNE1CDK2GSK3B | |
| SCHEMBL12045573 | 0.82 | POLB (0.37) | POLBGAANPSR1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |